Often used for:
Management of mild to moderate pain
What is propoxyphene?
Propoxyphene is an opioid analgesic that was previously used to treat pain, often combined with acetaminophen. It may cause sedation and other opioid-related effects.
Possible side effects
- Drowsiness
- Nausea or vomiting
- Slow breathing
- Low blood pressure
- Constipation
- Itching or hives
- Dizziness
- Mood changes
- Dry mouth
- Fainting or urinary retention
- Allergic reactions (rash, hives, itching, chills, fever, headache, muscle ache, shortness of breath, coughing, tightness in throat, swelling of face or neck)
- Not all patients experience these effects. Report all symptoms.
Tips for patients and families
- Discuss all instructions with the doctor or pharmacist.
- Many side effects lessen after a few days; contact the doctor if they worsen.
- Do not stop regular doses abruptly; the doctor may taper gradually.
- Use caution driving or operating machinery.
- Increase fluid and fiber intake and use stool softeners if needed for constipation.
- Inform the care team of all medicines, especially those that cause drowsiness or contain acetaminophen.
