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Often used for: Preventing or treating nausea and vomiting; stimulating appetite

What is dronabinol?

Dronabinol is a cannabinoid that helps prevent or treat chemotherapy-related nausea and vomiting and can improve appetite to prevent weight loss. Long-term use can be habit-forming, so patients may be monitored for changes in heart rate, blood pressure, mood, or behavior.

Dronabinol at home

  • Do not take more often or in higher amounts than prescribed.
  • This medicine may cause dizziness or drowsiness; avoid driving or hazardous activities until you know how it affects you.
  • Capsules: swallow whole and store in a cool place or refrigerator (do not freeze).
  • Oral liquid: measure with the supplied device, take with a full glass of water, store unopened bottles in the refrigerator, and after opening keep at room temperature or refrigerated; discard unused medicine after 6 weeks.
  • If a dose is missed, take it as soon as possible unless it is near the next dose; do not double doses.
  • Do not share this medicine and do not use past the expiration date.

Possible side effects

  • Dizziness or feeling lightheaded
  • Dry mouth
  • Sleepiness
  • Mood changes
  • Abdominal pain
  • Fatigue or weakness
  • Headache
  • Problems with thinking, focus, or memory
  • Confusion, strange thoughts, or hallucinations
  • Anxiety
  • Nausea and vomiting
  • Not all patients will experience these side effects. Report any symptoms to the care team.

Tips for families

  • Discuss all questions with your doctor or pharmacist.
  • For chemotherapy-related nausea, doses are often given 1–3 hours before treatment and then every 2–4 hours afterward (up to 4–6 doses per day).
  • For appetite stimulation, doses are usually given 1 hour before lunch and dinner; patients may track weight and food intake with help from a dietitian.
  • Avoid alcohol while taking this medicine.
  • Inform the care team if the patient is pregnant or breastfeeding.